Atypical Bilateral Fracture of the Femoral Diaphysis in Bisphosphonate Therapy

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منابع مشابه

Simultaneous Bilateral Atypical Femoral Fracture: Case Presentation

This type of fracture is related to the use of bisphosphonates (BFN), the first report was published in 2005 by Odvina [2]. In 2013 the American Society for Bone and Mineral Research (ASBMR) described the criteria for FFA diagnosis. These criteria were classified as major and minor (Table 1) [1], at least 4 major criteria are needed for FFA diagnosis; juveniles are not needed but are usually pr...

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Risk of atypical femoral fracture during and after bisphosphonate use

BACKGROUND AND PURPOSE Use of bisphosphonates in women is associated with higher risk of atypical femoral fractures. The risk in terms of timing of use and type of bisphosphonate, and in men, remains unclear. PATIENTS AND METHODS We reviewed radiographs of 5,342 Swedish women and men aged 55 years or more who had had a fracture of the femoral shaft in the 3-year period 2008-2010 (97% of those...

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Bilateral Atypical Femoral Fractures in a Patient with Multiple Myeloma Treated with Intravenous Bisphosphonate Therapy

Bisphosphonates are currently the standard approach to managing bone disease in multiple myeloma. Bisphosphonates have high bone affinity that inhibits osteoclastic activity and additionally reduces the growth factors released from malignant or osteoblastic cells, thereby impairing abnormal bone remodeling which leads to osteolysis. However, patients of multiple myeloma may be at a higher risk ...

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A Case Report of Long-Term Bisphosphonate Therapy and Atypical Stress Fracture of Bilateral Femur

Bisphosphonates are potent inhibitors of bone resorption and considered as a gold standard and are generally recommended as first-line therapy in patients with osteoporosis. Though bisphosphonates are shown to significantly reduce the risk of vertebral, non-vertebral and hip fractures, recent reports suggest a possible correlation between long-term bisphosphonate therapy and the occurrence of i...

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Subtrochanteric Femoral Insufficiency Fracture Following Bisphosphonate Therapy for Osseous Metastases

We present the case of an insufficiency fracture of the femoral shaft in a 61-year-old man who had received bisphosphonate therapy to reduce the fracture risk from lytic renal cell carcinoma metastases to the spine. Approximately 1.5 years after beginning monthly intravenous infusions of zoledronic acid (Zometa), the patient complained of persistent thigh pain. Radionuclide bone scan showed mil...

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ژورنال

عنوان ژورنال: Orthopedics & Traumatology

سال: 2012

ISSN: 0037-1033,1349-4333

DOI: 10.5035/nishiseisai.61.280